Phenibut HCl
Phenibut HCl is a derivative of the neurotransmitter GABA (gamma-aminobutyric acid) and is studied primarily as an anxiolytic and nootropic effects. Some reports suggest potential for cognitive enhancement and mood support, though clinical evidence is limited.
Chemical Properties
| Formal Name | 4-amino-3-phenylbutanoic acid hydrochloride. |
| CAS No: | 3060-41-1 |
| Synonym | Fenibut, PhGABA, Phenyl-GABA HCl |
| Molecular Formula | C10H13NO2.HCl |
| Molecular Weight | 215.7 g/mol |
| Appearance | Crystalline solid |
| Purity | 95% |
| Storage | Store in a cool, dry place at room temperature |
Mechanism of Action
Phenibut HCl has the potential to primarily bind to GABA-B receptors in the brain, which are inhibitory neurotransmitter receptors. It may also have some actions of GABA-B receptors and the dopamine system. This binding may potentially increase the inhibitory effects of GABA, leading to a reduction in neuronal excitability and producing calming and anxiolytic effects.
Potential Benefits
- Potential for Reduced anxiety: May have the potential to help alleviate feelings of anxiety by promoting a calming effect in the brain.
- Potential to Enhance cognitive function: May have the potential to improve focus, memory, and mental clarity.
- Has the potential to improve sleep quality: Research suggests it may help in achieving deeper and more restful sleep.
- Potential to elevate mood: It might potentially help boost overall mood and reduce symptoms of depression.
Clinical Research
Phenibut HCl has limited clinical research available, with most studies conducted in Russia. This is due to the lack of formal approval in regulated markets, which limits widespread clinical research outside Russia. Its safety and efficacy have not been well-established in broader scientific communities.
Phenibut HCl and Anxiety
Phenibut HCl is often studied to alleviate anxiety due to its ability to enhance GABA activity in the brain which calms the nervous system. This has the potential to result in reduced anxiety levels and a general feeling of relaxation.
Phenibut HCl and ADHD
Phenibut HCl is not widely researched for ADHD. Phenibut HCl may have the potential to help improve focus and cognitive function. By reducing anxiety and increasing mental clarity, it could potentially support focus. However, there is no clinical evidence supporting Phenibut use in ADHD. Some speculate about cognitive effects, but research is lacking
Phenibut HCl and Insomnia
Phenibut HCl may help improve sleep quality by promoting relaxation and reducing overactive thoughts that disturb sleep. Its potential calming effects in subjects make it a potential aid for those struggling with insomnia.
What is Phenibut HCl for?
Phenibut is widely being studied and used in Russia to relieve tension, anxiety, and fear, to improve sleep in psychosomatic or neurotic patients; as well as a pre- or post-operative medication.
Is Phenibut banned in the US?
In United States, Phenibut is not an FDA-approved drug. It is sometimes sold online, but the FDA has issued warnings about its use in supplements, also known by names such as Fenibut, Pbut, Noofen, and Brain Booster.
What are the side effects of Phenibut HCl?
Possible side effects include drowsiness, tolerance development, and withdrawal-like symptoms. Other risks include dependence, severe withdrawal symptoms (insomnia, tremors, irritability), rebound anxiety, seizures, and overdose when misused.
What is the shelf life of Phenibut HCl?
The shelf life of Phenibut HCl is typically 12-24 months when stored in a cool, dry place. Proper storage helps maintain its stability and potency.
How to store Phenibut HCl?
It is best to store this product in a cool, dry place away from direct sunlight. This helps extend the shelf life of the product.
Where to buy Phenibut HCl online?
PureRawz is a supplier that offers Phenibut HCl for research purposes. Each product includes reference materials for identification and purity verification. A Certificate of Analysis for identification, purity, and concentration is provided for every product by an independent third party. Free international shipping is available on orders over $100, with payment options such as PayPal and Bitcoin.
Note: In the Nootropics Powder category, PureRawz offers lab-tested formulations including Pterostilbene (Dimethylresveratrol), FLModafinil (CRL-40,940) among others.
Why do researchers study Phenibut?
Phenibut is studied for its potential anxiolytic and sedative properties, including possible applications in anxiety and insomnia, but it is not an approved treatment.
How does Phenibut potentially work in the brain of subjects?
Chemically, Phenibut is thought to work similarly to the neurotransmitter GABA (gamma-aminobutyric acid), which reduces neuronal excitability.
Summary
Phenibut HCl is a GABA analog studied primarily for its anxiolytic and nootropic effects. While it offers several potential research benefits such as anxiety reduction and improved sleep, more controlled studies are needed to confirm its safety and efficacy.
Disclaimer
This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By placing an order, you agree to our Terms and Conditions. If you are not 100% satisfied with the product you received, please contact us at support@purerawz.co
Our products are strictly for laboratory research use only and are not approved for human or veterinary consumption.



