PE-22-28 Peptide
PE-22-28 is a synthetic derivative of the naturally occurring peptide spadin. Spadin is a secreted peptide derived from sortilin. It is an antagonist of the TREK-1 (TWIK-related potassium channel) receptor. This is being studied in research models related to depression and neurodegenerative diseases.
Chemical Properties of PE-22-28 Peptide
| Product | PE-22-28 |
| Synonyms | Gly-Val-Ser-Trp-Gly-Leu-Arg-OH |
| Molecular Weight | 773.89 g/mol |
| Molecular Formula | C35H55N11O9 |
| CAS Number | 1801959-12-5 |
| Purity | ≥ 95% |
| Storage | -20 °C |
How does PE-22-28 work?
PE-22-28 is a small protein-like molecule that blocks the TREK-1 channel, a pathway linked to brain and mood control. Stopping TREK-1 may help brain cells become more active and improve connections between them.
Preclinical studies suggest it may support cell growth. It is being investigated in research settings for its potential role in brain-related conditions.
What are the potential benefits of PE-22-28?
Researchers are investigating PE-22-28 for its several potential benefits, including the following:
- PE-22-28 may help reduce stress and depression
- It may improve brain cell activity and connections
- PE-22-28 may support brain cell growth (neurogenesis)
- Research shows it may enhance mood and emotional stability
- It may protect brain cells from damage
- It is being explored in research for potential relevance to brain-related conditions
Note: It is strictly intended for research purposes and is not approved for human consumption.
PE-22-28 in Muscle Function Research
PE-22-28 blocks the TREK-1 channel, which may help regulate muscle activity. Researchers are investigating whether TREK-1 modulation by PE-22-28 influences muscle activity and relaxation in laboratory studies.
PE-22-28 in Depression Research
PE-22-28 is examined to increase brain cell activity and strengthen their connections. This process is linked to better mood regulation and reduced stress. Studies are exploring whether PE-22-28 influences mood regulation pathways by modulating brain chemistry. Researchers are exploring its possible effects in depression-related models.
PE-22-28 in Post-Stroke Studies
After a stroke, brain changes are associated with mood alterations. PE-22-28 is being studied in experimental models for its potential effects on neuronal recovery and post-stroke outcomes.
PE-22-28 in Neurodegenerative Research
PE-22-28 is being investigated in neurodegenerative research models to assess whether TREK-1 modulation influences neuronal survival and growth. Researchers are investigating whether supporting brain function with PE-22-28 may have relevance in models of neurodegenerative conditions.
Where to Buy PE-22-28 Peptide Online for Research Purposes?
If you want to buy PE-22-28 for research purposes, PureRawz is a reliable option.
We provide reference materials with every product we offer. Each of our products comes with an independent, third-party-issued Certificate of Analysis for identification, purity, and concentration.
Note:PureRawz expands its peptide unconstituted category with high-quality formulations like, PAL-GHK, Spartan 2 (Mod GRF 1-29/CJC-1295 No Dac GHRP-2) and many more.
Is PE-22-28 legal?
The FDA has not approved PE-22-28 as a drug. However, it is available for scientific research. Always check the local laws of your particular region before purchasing it.
FAQs
Is PE-22-28 safe for human use?
No, it has not been approved for human or veterinary use by the FDA. It is used solely for research purposes.
Is PE-22-28 available for treatment?
Currently, PE-22-28 is still in the research phase and is not approved for medical use. It is being studied in preclinical and experimental models for its potential biological effects.
Are there any side effects of PE-22-28?
The safety profile and potential side effects of PE-22-28 remain undefined, as it is still under investigation.
How should this product be stored?
Store at –20°C, protected from light and moisture. This helps extend the shelf life of the product.
Disclaimer
This information is provided for educational purposes only and should not be considered medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions. If you are not 100% satisfied with the product you received, please contact us at support@purerawz.co
ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human use

