FOXO4-DRI (Proxofim)
FOXO4-DRI, also called Proxofim, is a peptide made by scientists to study how old or damaged cells can be removed. These cells are called senescent cells. They stop dividing but persist in tissues and may contribute to age-related dysfunction.
PureRawz is offering FOXO4-DRI only for laboratory and research use. Not for human use.
What is FOXO4-DRI (Proxofim)?
FOXO4-DRI, or Proxofim, is a lab-made peptide. It may play a role in aging and senescence studies. The main idea is that this peptide can block the meeting between the FOXO4 protein and another important guardian protein called p53. When these two connect, old or damaged cells, called senescent cells, stay alive even though they no longer divide.
Chemical Formula
| Chemical Name | FOXO4-DRI |
| CAS No | 2460055-10-9 |
| Synonym | Forkhead box protein O4, Proxofim, AFX, AFX1 |
| Molecular Formula | C228H388N86O64 |
| Molecular Weight | 5358.05 g/mol |
| Appearance | Solid |
| Color | White to Off-white |
What are its Potential Research Applications?
Research on FOXO4-DRI is still early. Most studies are preclinical. But available data suggest some important directions:
- FOXO4-DRI may support the clearance of senescent cells, possibly improve tissue repair, and promote healthier aging.
- Some studies show that FOXO4-DRI may help protect brain cells, which is important when looking at age-related brain decline.
- Researchers are studying its possible link to strength and endurance.
- FOXO4-DRI may also lower cell stress in blood vessel tissues of test subjects.
All these results come only from early studies, using animals or cell models in the lab. How it works in humans is still not known, and its safety and effects are not proven.
Mechanism of Action
The main action is simple:
FOXO4 normally binds p53 inside senescent cells. When FOXO4 binds to p53, the cell remains alive but remains damaged. FOXO4-DRI is made to block that binding, and p53 is free to signal the cell for apoptosis.
In this way, FOXO4-DRI may help researchers study how old or harmful cells can be cleared. This gives scientists a model to explore cleaner tissues and possible links to healthy aging.
Conclusion
FOXO4-DRI (Proxofim) studies suggest it may have potential in areas like anti-aging, muscle repair, and heart function. But all results so far come only from preclinical studies.
It is not approved for human or veterinary use. PureRawz provides this compound strictly for laboratory and scientific research, and each product comes with a Certificate of Analysis to confirm purity and identity
FAQs
What does the FOXO4-DRI peptide do?
It may block FOXO4 and p53 interaction, allowing senescent cells to be cleared in lab studies.
What is the difference between FOXO4 and FOXO4-DRI?
FOXO4 is a natural protein. FOXO4-DRI is a synthetic peptide designed to stop FOXO4 binding to p53.
What is the FOXO4-DRI sequence?
The sequence is: H-Pyr-Glu-Leu-Arg-Ala-Leu-Asn-Ser-Ser-OH.
Disclaimer
FOXO4-DRI and all products from PureRawz are sold only for laboratory and scientific research. They are not for human or animal use. Please check and verify all information yourself before making any purchase.
By ordering, you accept our Terms and Conditions. If the product you receive is not satisfactory, please contact us at support@purerawz.co
ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human usage.

